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Of the 1,578 cases of overdose involving fluoxetine hydrochloride, alone or with other drugs, reported from this population, there were 195 deaths.
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They may also hide certain signs of low blood sugar and make it more difficult to notice angiotensin-converting enzyme ace inhibitors eg, enalapril , azole antifungals eg, miconazole, ketoconazole , chloramphenicol, clarithromycin, clofibrate, disopyramide, fenfluramine, fluoxetine, insulin, monoamine oxidase inhibitors maois eg, phenelzine , nonsteroidal anti-inflammatory drugs nsaids eg, ibuprofen , phenylbutazone, probenecid, quinolone antibiotics eg, ciprofloxacin , salicylates eg, aspirin , and sulfonamides eg, sulfamethoxazole because the risk of low blood sugar may be increased calcium channel blockers eg, diltiazem , corticosteroids eg, prednisone , decongestants eg, pseudoephedrine , diazoxide, diuretics eg, furosemide, hydrochlorothiazide , estrogens, hormonal contraceptives eg, birth control pills , isoniazid, niacin, phenothiazines eg, promethazine , phenytoin, rifamycins eg, rifampin , sympathomimetics eg, albuterol, epinephrine , or thyroid supplements eg, levothyroxine because they may decrease duetact s effectiveness, resulting in high blood sugar gemfibrozil because blood sugar may be increased or decreased anticoagulants eg, warfarin because their effectiveness may be decreased or the risk of their side effects may be increased by duetact.
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Because fluoxetine s metabolism, like that of a number of other compounds including tcas and other ssris, involves the cyp2d6 system, concomitant therapy with drugs also metabolized by this enzyme system such as the tcas may lead to drug interactions see drug interactions under precautions .
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Less than a week the usual starting dose for fluoxetine prozac is 20 mg, so you were on a very low dose, so after 6 doses there is not very much med in your body.
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Thus, this study suggests that drugs which inhibit cyp2d6, such as certain ssris, including fluoxetine, will produce elevated plasma levels of thioridazine.
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